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Paperguide (operating on ChatwithPDF.ai) is an artificial intelligence research platform designed for scientific literature reviews, systematic evidence synthesis, and academic reference management. The software allows researchers to discover, analyze, and synthesize findings across an index of more than 200 million cited scientific papers. The platform provides structured workflows for conducting auditable systematic reviews adhering to PRISMA guidelines, an integrated reference manager supporting Zotero and Mendeley imports, citation-grounded AI writing tools, and autonomous research agents that extract data across multiple studies into structured tables. The tool is tailored for academic researchers, post-graduate students, medical scientists, pharmaceutical teams, and research institutions. It operates on a freemium model offering free basic features alongside paid subscription tiers and enterprise plans for research organizations.